For the intro and root cause of polycystic ovary syndrome (PCOS) please read yesterday’s post (same title, part 1). Here we’ll just briefly lay out the main premise that PCOS is caused and worsened by eating habits – consuming too much sugar (processed carbs count as well) or eating too often so your blood sugar doesn’t get a chance to fall. The constant overflow of insulin subsequently leads to insulin resistance and metabolic syndrome which regularly accompany PCOS and combined lead to infertility which could be reversed by lifestyle choices. Today we go deeper into the chemistry of what happens in the body with PCOS.
There is a large correlation with obesity, PCOS and infertility since obesity, gaining weight uncontrollably or troubles losing it mean there is a big chance you have an insulin problem. Insulin is responsible for converting excess blood sugar (so anything you don’t need) into fat to be stored as reserves. Losing weight by managing when and what you eat (intermittent fasting , keto, low carb) almost certainly means you’ve begun to regulate your blood sugar as well. So as the pounds fall off the PCOS symptoms get better as well. The masculinizing features, such as acne, facial or body hair overgrowth and male pattern baldness accompanying PCOS in a severe or milder forms, are a result of a hormone imbalance – an excess of testosterone. Testosterone is produced by the adrenal glands and ovaries and in PCOS the execs testosterone is coming from the ovaries. Usually the excess testosterone would be binded to a protein called SHBG (sex hormone binding globulin) produced in the liver. Liver is the first place where insulin stores excess sugars and non-alcoholic fatty liver often accompanies PCOS impairing the production of SHBG and the free flowing unbound testosterone just circulates in the blood stream, resulting in more masculinizing features. The higher the insulin in the body, lower the levels of SHBG and higher the levels of free testosterone meaning more severe masculine traits.
The reason why women can’t get pregnant with PCOS is not that they don’t have eggs. They do but the eggs are just stuck in one developmental phase and never mature enough to be ovulated and travel to the uterus. The eggs are, in what is called, follicular arrest. The normal developed egg responds to the surge of LH hormone when it is about 9.5 mm, while in the body with excess insulin the follicle becomes overly responsive too early at 4mm and never fully develops. It stops at about 8mm while it needs to be 1-1.5 cm to be ovulated, and it’s all caused by hyperinsulinemia. So Clomid, birth control pills and IV are not the solution. Metformin which is given to diabetics is also sometimes used and is the one that makes a bit more sense since it lowers insulin, but you’re still not treating the thing that got you there – Eating too much carbs and eating far too often.
PCOS can be fixed naturally and with no drugs. Please share this with any woman struggling or feeling that this might be going on in her body.